L-Hydroxyproline CAS NO.51-35-4

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L-Hydroxyproline Basic information

Product Name:    L-Hydroxyproline
Synonyms:    H-HYP-OH;H-HYP-OH (TRANS);H-L-HYDROXYPROLINE;H-L-HYP-OH;H-TRANS-HYP-OH;HYDROXYPROLINE;HYDROXY-L-PROLINE;HYDROXY-L-PROLINE, TRANS-4-
CAS:    51-35-4
MF:    C5H9NO3
MW:    131.13
EINECS:    200-091-9

L-Hydroxyproline Chemical Properties

Melting point     273 °C (dec.)(lit.)
alpha     -75.5 º (c=5, H2O)
Boiling point     242.42°C (rough estimate)
density     1.3121 (rough estimate)
vapor density     4.5 (vs air)
refractive index     -75.5 ° (C=4, H2O)
storage temp.     Store at RT.
solubility     H2O: 50 mg/mL
form     Crystals or Crystalline Powder
pka    1.82, 9.66(at 25℃)
color     White
PH    5.5-6.5 (50g/l, H2O, 20℃)
Odor    Odorless
optical activity    [α]25/D 75.6°, c = 1 in H2O
Water Solubility     357.8 g/L (20 º C)

L-Hydroxyproline Usage And Synthesis

Uses    A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.
Uses    A versatile reagent for the synthesis of neuroexcitatory kainoids and antifungal echinocandins.
Uses    hydroxyproline is a skin-conditioning amino acid. It is a component of collagen.