Methyl Salicylate CAS NO.119-36-8

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Methyl salicylate Basic information
Product Name:    Methyl salicylate
Synonyms:    Birch-Me, AR,99%;Methyl Salicylate;Methyl salicylate In stock Factory;Methyl salicylate/2-hydroxy-benzoicacimethylester;WINTERGREEN;WINTERGREEN OIL, SYNTHETIC;SYNTHETIC OIL OF WINTERGREEN;SWEET BIRCH OIL
CAS:    119-36-8
MF:    C8H8O3
MW:    152.15
EINECS:    204-317-7

Methyl salicylate Chemical Properties
Melting point     -8 °C
Boiling point     222 °C(lit.)
density     1.174 g/mL at 25 °C(lit.)
vapor density     5.26 (vs air)
vapor pressure     1 mm Hg ( 54 °C)
refractive index     n20/D 1.536(lit.)
FEMA     2745 | METHYL SALICYLATE
Fp     226 °F
solubility     Very slightly soluble in water, miscible with ethanol (96 per cent) and with fatty and essential oils.
form     Liquid
pka    pKa 9.90 (Uncertain)
color     Clear colorless to pale yellow
Water Solubility     0.07 g/100 mL (20 ºC)

Uses    Methyl salicylate occurs in the leaves ofGaultheria procumbens L. and in the barkof Betulaceae. It is produced by esterificationof salicylic acid with methanol. It is used inperfumery and as a flavoring agent.

Uses    In high concentrations as a rubefacient in deep heating liniments (such as Bengay) to treat joint and muscular pain. Randomised double blind trial reviews report evidence of its effectiveness that is weak, but stronger for acute pain than chronic pain, and that effectiveness may be due entirely to counter-irritation. However, in the body it metabolizes into salicylates, including salicylic acid, a known NSAID.
In low concentrations as a flavoring agent (no more than 0.04%; it is toxic).
providing fragrance to various products and as an odor-masking agent for some organophosphate pesticides. If used excessively, it can cause stomach and kidney problems.
Attracting male orchid bees, who apparently gather the chemical to synthesize pheromones; it is commonly used as bait to attract and collect these bees for study.
Clear plant or animal tissue samples of color, and as such is useful for microscopy and immunohistochemistry when excess pigments obscure structures or block light in the tissue being examined. This clearing generally only takes a few minutes, but the tissue must first be dehydrated in alcohol.

Methyl salicylate is among the compounds that attract male orchid bees, who apparently gather the chemical to synthesize pheromones; it is commonly used as bait to attract and collect these bees for study.

Uses    Methyl salicylate is an organic ester that is commonly produced naturally by wintergreens. Methyl salicylate is utilize as a anti-herbivore defense system in various plants that produces it. Methyl sa licylate is also used in high concentrations as a rubefacient to treat joint, muscular pain and acute pain. Methyl slicylate is also used as a flavoring agent and often used to provide fragrance to pr oducts.

Uses    Potent inhibitor of ornithine decarboxylase